Developmentally Regulated Glycosylation of the CD8αβ Coreceptor Stalk Modulates Ligand Binding

نویسندگان

  • Anne Marie Moody
  • Daniel Chui
  • Pedro A Reche
  • John J Priatel
  • Jamey D Marth
  • Ellis L Reinherz
چکیده

stalk being 10–13 residues shorter than that of the 45-residue CD8␣ stalk (Kern et al., 1998). The presence of numerous proline residues plus O-glycans in both stalks indicate that they assume an extended conformation (Classon et al., 1992). CD8 glycan adducts change dur

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عنوان ژورنال:
  • Cell

دوره 107  شماره 

صفحات  -

تاریخ انتشار 2001